Cis-splicing and Translation of the Pre-Trans-splicing Molecule Combine With Efficiency in Spliceosome-mediated RNA Trans-splicing

Muscular dystrophies are a group of genetically distinct diseases for which no treatment exists. While gene transfer approach is being tested for several of these diseases, such strategies can be hampered when the size of the corresponding complementary DNA (cDNA) exceeds the packaging capacity of a...

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Bibliografiske detaljer
Main Authors: Monjaret, François, Bourg, Nathalie, Suel, Laurence, Roudaut, Carinne, Le Roy, Florence, Richard, Isabelle, Charton, Karine
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048894/
https://ncbi.nlm.nih.gov/pubmed/24618805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.35
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