Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development

RNA editing and splicing are the two major processes that dynamically regulate human transcriptome diversity. Despite growing evidence of crosstalk between RNA editing enzymes (mainly ADAR1) and splicing machineries, detailed mechanistic explanations and their biological importance in diseases, such...

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Publicat a:Nat Commun
Autors principals: Tang, Sze Jing, Shen, Haoqing, An, Omer, Hong, HuiQi, Li, Jia, Song, Yangyang, Han, Jian, Tay, Daryl Jin Tai, Ng, Vanessa Hui En, Bellido Molias, Fernando, Leong, Ka Wai, Pitcheshwar, Priyankaa, Yang, Henry, Chen, Leilei
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005744/
https://ncbi.nlm.nih.gov/pubmed/32034135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14621-5
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