GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor‐suppressor gene TGFβR2 in colorectal cancer

Chromosome 7q (Ch.7q) is clonally amplified in colorectal cancer (CRC). We aimed to identify oncogenes on Ch.7q that are overexpressed through DNA copy number amplification and determine the biological and clinical significance of these oncogenes in CRC. We identified general transcription factor 2I...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Nambara, Sho, Masuda, Takaaki, Kobayashi, Yuta, Sato, Kuniaki, Tobo, Taro, Koike, Kensuke, Noda, Miwa, Ogawa, Yushi, Kuroda, Yousuke, Ito, Shuhei, Eguchi, Hidetoshi, Sugimachi, Keishi, Mimori, Koshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004548/
https://ncbi.nlm.nih.gov/pubmed/31758608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14248
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