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GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor‐suppressor gene TGFβR2 in colorectal cancer

Chromosome 7q (Ch.7q) is clonally amplified in colorectal cancer (CRC). We aimed to identify oncogenes on Ch.7q that are overexpressed through DNA copy number amplification and determine the biological and clinical significance of these oncogenes in CRC. We identified general transcription factor 2I...

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Vydáno v:Cancer Sci
Hlavní autoři: Nambara, Sho, Masuda, Takaaki, Kobayashi, Yuta, Sato, Kuniaki, Tobo, Taro, Koike, Kensuke, Noda, Miwa, Ogawa, Yushi, Kuroda, Yousuke, Ito, Shuhei, Eguchi, Hidetoshi, Sugimachi, Keishi, Mimori, Koshi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004548/
https://ncbi.nlm.nih.gov/pubmed/31758608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14248
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