Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer

Yes-associated protein 1 (YAP1) acts as an oncogene through dephosphorylation and nuclear translocation, and nuclear accumulation of YAP1 is associated with poor prognosis in gastric cancer (GC). We previously identified ivermectin, an antiparasitic drug, as a YAP1 inhibitor. Here, we aimed to clari...

Full description

Saved in:
Bibliographic Details
Published in:Oncotarget
Main Authors: Nambara, Sho, Masuda, Takaaki, Nishio, Miki, Kuramitsu, Shotaro, Tobo, Taro, Ogawa, Yushi, Hu, Qingjiang, Iguchi, Tomohiro, Kuroda, Yousuke, Ito, Shuhei, Eguchi, Hidetoshi, Sugimachi, Keishi, Saeki, Hiroshi, Oki, Eiji, Maehara, Yoshihiko, Suzuki, Akira, Mimori, Koshi
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746098/
https://ncbi.nlm.nih.gov/pubmed/29296196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22587
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items