Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer

Yes-associated protein 1 (YAP1) acts as an oncogene through dephosphorylation and nuclear translocation, and nuclear accumulation of YAP1 is associated with poor prognosis in gastric cancer (GC). We previously identified ivermectin, an antiparasitic drug, as a YAP1 inhibitor. Here, we aimed to clari...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Nambara, Sho, Masuda, Takaaki, Nishio, Miki, Kuramitsu, Shotaro, Tobo, Taro, Ogawa, Yushi, Hu, Qingjiang, Iguchi, Tomohiro, Kuroda, Yousuke, Ito, Shuhei, Eguchi, Hidetoshi, Sugimachi, Keishi, Saeki, Hiroshi, Oki, Eiji, Maehara, Yoshihiko, Suzuki, Akira, Mimori, Koshi
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746098/
https://ncbi.nlm.nih.gov/pubmed/29296196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22587
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