miR-146a Polymorphism (rs2910164) Predicts Colorectal Cancer Patients’ Susceptibility to Liver Metastasis

miR-146a plays important roles in cancer as it directly targets NUMB, an inhibitor of Notch signaling. miR-146a is reportedly regulated by a G>C polymorphism (SNP; rs2910164). This polymorphism affects various cancers, including colorectal cancer (CRC). However, the clinical significance of miR-1...

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Veröffentlicht in:PLoS One
Hauptverfasser: Iguchi, Tomohiro, Nambara, Sho, Masuda, Takaaki, Komatsu, Hisateru, Ueda, Masami, Kidogami, Shinya, Ogawa, Yushi, Hu, Qingjiang, Sato, Kuniaki, Saito, Tomoko, Hirata, Hidenari, Sakimura, Shotaro, Uchi, Ryutaro, Hayashi, Naoki, Ito, Shuhei, Eguchi, Hidetoshi, Sugimachi, Keishi, Maehara, Yoshihiko, Mimori, Koshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100922/
https://ncbi.nlm.nih.gov/pubmed/27824903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165912
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