Impact of HSD17B13 rs72613567 genotype on hepatic decompensation and mortality in patients with portal hypertension

BACKGROUND & AIMS: The loss‐of‐function rs72613567 T > TA‐variant in the 17β‐hydroxysteroid dehydrogenase 13 (HSD17B13) gene might protect from alcoholic and non‐alcoholic fatty liver disease (ALD/NAFLD) and associated fibrosis/cirrhosis. We investigated the impact of the T > TA‐variant on...

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Dettagli Bibliografici
Pubblicato in:Liver Int
Autori principali: Scheiner, Bernhard, Stättermayer, Albert F., Schwabl, Philipp, Bucsics, Theresa, Paternostro, Rafael, Bauer, David, Simbrunner, Benedikt, Schmidt, Ralf, Marculescu, Rodrig, Ferlitsch, Arnulf, Peck‐Radosavljevic, Markus, Pinter, Mathias, Trauner, Michael, Reiberger, Thomas, Ferenci, Peter, Mandorfer, Mattias
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Genetics and Rare Liver Diseases
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003973/
https://ncbi.nlm.nih.gov/pubmed/31967400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14304
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