Impact of farnesoid X receptor single nucleotide polymorphisms on hepatic decompensation and mortality in cirrhotic patients with portal hypertension

BACKGROUND AND AIM: The nuclear farnesoid X receptor (FXR) regulates critical pathways of hepatic metabolism, inflammation, and gut mucosal barrier. Thus, we investigated the association of FXR‐single nucleotide polymorphism (SNPs) with hepatic decompensation and liver‐related mortality in patients...

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Bibliografiska uppgifter
I publikationen:J Gastroenterol Hepatol
Huvudupphovsmän: Semmler, Georg, Simbrunner, Benedikt, Scheiner, Bernhard, Schwabl, Philipp, Paternostro, Rafael, Bucsics, Theresa, Stättermayer, Albert Friedrich, Bauer, David, Pinter, Matthias, Ferenci, Peter, Trauner, Michael, Mandorfer, Mattias, Reiberger, Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Clinical Hepatology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973125/
https://ncbi.nlm.nih.gov/pubmed/31062417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jgh.14700
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