Impact of farnesoid X receptor single nucleotide polymorphisms on hepatic decompensation and mortality in cirrhotic patients with portal hypertension

BACKGROUND AND AIM: The nuclear farnesoid X receptor (FXR) regulates critical pathways of hepatic metabolism, inflammation, and gut mucosal barrier. Thus, we investigated the association of FXR‐single nucleotide polymorphism (SNPs) with hepatic decompensation and liver‐related mortality in patients...

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Detalhes bibliográficos
Publicado no:J Gastroenterol Hepatol
Main Authors: Semmler, Georg, Simbrunner, Benedikt, Scheiner, Bernhard, Schwabl, Philipp, Paternostro, Rafael, Bucsics, Theresa, Stättermayer, Albert Friedrich, Bauer, David, Pinter, Matthias, Ferenci, Peter, Trauner, Michael, Mandorfer, Mattias, Reiberger, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Clinical Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973125/
https://ncbi.nlm.nih.gov/pubmed/31062417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jgh.14700
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