Impact of farnesoid X receptor single nucleotide polymorphisms on hepatic decompensation and mortality in cirrhotic patients with portal hypertension

BACKGROUND AND AIM: The nuclear farnesoid X receptor (FXR) regulates critical pathways of hepatic metabolism, inflammation, and gut mucosal barrier. Thus, we investigated the association of FXR‐single nucleotide polymorphism (SNPs) with hepatic decompensation and liver‐related mortality in patients...

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Vydáno v:J Gastroenterol Hepatol
Hlavní autoři: Semmler, Georg, Simbrunner, Benedikt, Scheiner, Bernhard, Schwabl, Philipp, Paternostro, Rafael, Bucsics, Theresa, Stättermayer, Albert Friedrich, Bauer, David, Pinter, Matthias, Ferenci, Peter, Trauner, Michael, Mandorfer, Mattias, Reiberger, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Clinical Hepatology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973125/
https://ncbi.nlm.nih.gov/pubmed/31062417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jgh.14700
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