Impact of HSD17B13 rs72613567 genotype on hepatic decompensation and mortality in patients with portal hypertension

BACKGROUND & AIMS: The loss‐of‐function rs72613567 T > TA‐variant in the 17β‐hydroxysteroid dehydrogenase 13 (HSD17B13) gene might protect from alcoholic and non‐alcoholic fatty liver disease (ALD/NAFLD) and associated fibrosis/cirrhosis. We investigated the impact of the T > TA‐variant on...

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Publicat a:Liver Int
Autors principals: Scheiner, Bernhard, Stättermayer, Albert F., Schwabl, Philipp, Bucsics, Theresa, Paternostro, Rafael, Bauer, David, Simbrunner, Benedikt, Schmidt, Ralf, Marculescu, Rodrig, Ferlitsch, Arnulf, Peck‐Radosavljevic, Markus, Pinter, Mathias, Trauner, Michael, Reiberger, Thomas, Ferenci, Peter, Mandorfer, Mattias
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Genetics and Rare Liver Diseases
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003973/
https://ncbi.nlm.nih.gov/pubmed/31967400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14304
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