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GBT1118, a compound that increases the oxygen affinity of hemoglobin, improves survival in murine hypoxic acute lung injury

Acute respiratory distress syndrome (ARDS) is characterized by lung inflammation and pulmonary edema, leading to arterial hypoxemia and death if the hypoxemia is severe. Strategies to correct hypoxemia have the potential to improve clinical outcomes in ARDS. The goal of this study was to evaluate th...

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Veröffentlicht in:J Appl Physiol (1985)
Hauptverfasser: Putz, Nathan D., Shaver, Ciara M., Dufu, Kobina, Li, Chien-Ming, Xu, Qing, Hutchaleelaha, Athiwat, Lehrer-Graiwer, Josh, Majka, Susan M., Ware, Lorraine B., Bastarache, Julie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002864/
https://ncbi.nlm.nih.gov/pubmed/29357510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00079.2017
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