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An IgG1 version of the Anti-Transferrin Receptor 1 Antibody ch128.1 Shows Significant Anti-tumor Activity Against Different Xenograft Models of Multiple Myeloma: A Brief Communication

The transferrin receptor 1 (TfR1) is a meaningful target for antibody-based cancer therapy given its overexpression on malignant cells and its central role in cancer pathology. We previously developed a mouse/human chimeric IgG3 targeting human TfR1 (ch128.1), which exhibits significant anti-tumor a...

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Dettagli Bibliografici
Pubblicato in:J Immunother
Autori principali: Daniels-Wells, Tracy R., Candelaria, Pierre V., Leoh, Lai Sum, Nava, Miguel, Martínez-Maza, Otoniel, Penichet, Manuel L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002290/
https://ncbi.nlm.nih.gov/pubmed/31693515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000304
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