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Antibodies Targeting the Transferrin Receptor 1 (TfR1) as Direct Anti-cancer Agents

The transferrin receptor 1 (TfR1), also known as cluster of differentiation 71 (CD71), is a type II transmembrane glycoprotein that binds transferrin (Tf) and performs a critical role in cellular iron uptake through the interaction with iron-bound Tf. Iron is required for multiple cellular processes...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Candelaria, Pierre V., Leoh, Lai Sum, Penichet, Manuel L., Daniels-Wells, Tracy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010148/
https://ncbi.nlm.nih.gov/pubmed/33815364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.607692
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