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An IgG1 version of the Anti-Transferrin Receptor 1 Antibody ch128.1 Shows Significant Anti-tumor Activity Against Different Xenograft Models of Multiple Myeloma: A Brief Communication
The transferrin receptor 1 (TfR1) is a meaningful target for antibody-based cancer therapy given its overexpression on malignant cells and its central role in cancer pathology. We previously developed a mouse/human chimeric IgG3 targeting human TfR1 (ch128.1), which exhibits significant anti-tumor a...
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| 發表在: | J Immunother |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002290/ https://ncbi.nlm.nih.gov/pubmed/31693515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000304 |
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