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SIRT1 Mediates Septic Cardiomyopathy in a Murine Model of Polymicrobial Sepsis

BACKGROUND: Cardiac dysfunction, a common complication from severe sepsis, is associated with increased morbidity and mortality. However, the molecular mechanisms of septic cardiac dysfunction are poorly understood. SIRT1, a member of the sirtuin family of NAD+-dependent protein deacetylases, is an...

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Bibliografiska uppgifter
I publikationen:Shock
Huvudupphovsmän: Smith, Lane M., Yoza, Barbara K., Hoth, J. Jason, McCall, Charles E., Vachharajani, Vidula
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002289/
https://ncbi.nlm.nih.gov/pubmed/31393272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001429
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