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BHLHE40 promotes T(H)2 cell-mediated anti-helminth immunity and reveals cooperative CSF2RB family cytokines

The transcription factor BHLHE40 is an emerging regulator of the immune system. Recent studies suggest that BHLHE40 regulates type 2 immunity, but this has not been demonstrated in vivo. We found that BHLHE40 is required in T cells for a protective T(H)2 cell response in mice infected with the helmi...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Jarjour, Nicholas N., Bradstreet, Tara R., Schwarzkopf, Elizabeth A., Cook, Melissa E., Lai, Chin-Wen, Huang, Stanley Ching-Cheng, Taneja, Reshma, Stappenbeck, Thaddeus S., Van Dyken, Steven J., Urban, Joseph F., Edelson, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002269/
https://ncbi.nlm.nih.gov/pubmed/31900338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900978
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