Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection

The cytokine IL-10 antagonizes pathways that control Mycobacterium tuberculosis (Mtb) infection. Nevertheless, the impact of IL-10 during Mtb infection has been difficult to decipher because loss-of-function studies in animal models have yielded only mild phenotypes. We have discovered that the tran...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Huynh, Jeremy P., Lin, Chih-Chung, Kimmey, Jacqueline M., Jarjour, Nicholas N., Schwarzkopf, Elizabeth A., Bradstreet, Tara R., Shchukina, Irina, Shpynov, Oleg, Weaver, Casey T., Taneja, Reshma, Artyomov, Maxim N., Edelson, Brian T., Stallings, Christina L.
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2018
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028511/
https://ncbi.nlm.nih.gov/pubmed/29773644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171704
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