IL-1–induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation

The features that define autoreactive T helper (Th) cell pathogenicity remain obscure. We have previously shown that Th cells require the transcription factor Bhlhe40 to mediate experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. Here, using Bhlhe40 reporter mice an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Lin, Chih-Chung, Bradstreet, Tara R., Schwarzkopf, Elizabeth A., Jarjour, Nicholas N., Chou, Chun, Archambault, Angela S., Sim, Julia, Zinselmeyer, Bernd H., Carrero, Javier A., Wu, Gregory F., Taneja, Reshma, Artyomov, Maxim N., Russell, John H., Edelson, Brian T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2016
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749922/
https://ncbi.nlm.nih.gov/pubmed/26834156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150568
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg