Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation

T(H)1 and T(H)17 cells mediate neuroinflammation in experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. Pathogenic T(H) cells in EAE must produce the pro-inflammatory cytokine granulocyte-macrophage colony stimulating factor (GM-CSF). T(H) cell pathogenicity in EAE...

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Autori principali: Lin, Chih-Chung, Bradstreet, Tara R., Schwarzkopf, Elizabeth A., Sim, Julia, Carrero, Javier A., Chou, Chun, Cook, Lindsey E., Egawa, Takeshi, Taneja, Reshma, Murphy, Theresa L., Russell, John H., Edelson, Brian T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016562/
https://ncbi.nlm.nih.gov/pubmed/24699451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4551
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