IL-1–induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation

The features that define autoreactive T helper (Th) cell pathogenicity remain obscure. We have previously shown that Th cells require the transcription factor Bhlhe40 to mediate experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. Here, using Bhlhe40 reporter mice an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Lin, Chih-Chung, Bradstreet, Tara R., Schwarzkopf, Elizabeth A., Jarjour, Nicholas N., Chou, Chun, Archambault, Angela S., Sim, Julia, Zinselmeyer, Bernd H., Carrero, Javier A., Wu, Gregory F., Taneja, Reshma, Artyomov, Maxim N., Russell, John H., Edelson, Brian T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2016
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749922/
https://ncbi.nlm.nih.gov/pubmed/26834156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150568
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak