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An Emerging Regulatory Role for the Tumor Microenvironment in the DNA Damage Response to Double-Strand Breaks

Radiation, alkylating agents, and platinum-based chemotherapy treatments eliminate cancer cells through the induction of excessive DNA damage. The resultant DNA damage challenges the cancer cell’s DNA repair capacity. Among the different types of DNA damage induced in cells, double-strand breaks (DS...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer Res
Autori principali: Lama-Sherpa, Tshering D., Shevde, Lalita A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002210/
https://ncbi.nlm.nih.gov/pubmed/31676722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0665
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