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Physiological Roles of DNA Double-Strand Breaks

Genomic integrity is constantly threatened by sources of DNA damage, internal and external alike. Among the most cytotoxic lesions is the DNA double-strand break (DSB) which arises from the cleavage of both strands of the double helix. Cells boast a considerable set of defences to both prevent and r...

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Detalhes bibliográficos
Publicado no:J Nucleic Acids
Main Authors: Khan, Farhaan A., Ali, Syed O.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664317/
https://ncbi.nlm.nih.gov/pubmed/29181194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6439169
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