Evaluation of antihypertensive drugs in combination with enzyme replacement therapy in mice with Pompe disease

Pompe disease is caused by the deficiency of lysosomal acid α-glucosidase (GAA) leading to progressive myopathy. Enzyme replacement therapy (ERT) with recombinant human (rh) GAA has limitations, including inefficient uptake of rhGAA in skeletal muscle linked to low cation-independent mannose-6-phosp...

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Vydáno v:Mol Genet Metab
Hlavní autoři: Han, Sang-oh, Haynes, Alexina C., Li, Songtao, Abraham, Dennis M., Kishnani, Priya S., Steet, Richard, Koeberl, Dwight D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002209/
https://ncbi.nlm.nih.gov/pubmed/31645300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2019.10.005
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