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Evaluation of antihypertensive drugs in combination with enzyme replacement therapy in mice with Pompe disease
Pompe disease is caused by the deficiency of lysosomal acid α-glucosidase (GAA) leading to progressive myopathy. Enzyme replacement therapy (ERT) with recombinant human (rh) GAA has limitations, including inefficient uptake of rhGAA in skeletal muscle linked to low cation-independent mannose-6-phosp...
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| Pubblicato in: | Mol Genet Metab |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002209/ https://ncbi.nlm.nih.gov/pubmed/31645300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2019.10.005 |
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