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Leptin induces immunosenescence in human B cells

Leptin is an adipokine secreted primarily by the adipocytes. Leptin has endocrine and immune functions and increases the secretion of pro-inflammatory cytokines by immune cells. Here we show that incubation of B cells from young lean individuals with leptin increases the frequencies of pro-inflammat...

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Detalles Bibliográficos
Publicado en:Cell Immunol
Main Authors: Frasca, Daniela, Diaz, Alain, Romero, Maria, Blomberg, Bonnie B.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002206/
https://ncbi.nlm.nih.gov/pubmed/31831137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2019.103994
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