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Age effects on B cells and humoral immunity in humans
Both humoral and cellular immune responses are impaired in aged individuals, leading to decreased vaccine responses. Although T cell defects occur, defects in B cells play a significant role in age-related humoral immune changes. The ability to undergo class switch recombination (CSR), the enzyme fo...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040253/ https://ncbi.nlm.nih.gov/pubmed/20728581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2010.08.004 |
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