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High TNF-α levels in resting B cells negatively correlate with their response

Aging significantly decreases the influenza vaccine-specific response as we and others have previously shown. Based on our previous data in aged mice, we hypothesize that the inflammatory status of the individual and of B cells themselves would impact B cell function. We here show that the ability t...

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Bibliographic Details
Main Authors: Frasca, Daniela, Diaz, Alain, Romero, Maria, Landin, Ana Marie, Blomberg, Bonnie B.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989457/
https://ncbi.nlm.nih.gov/pubmed/24440385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.01.004
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