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The generation of memory B cells is maintained, but the antibody response is not, in the elderly after repeated influenza immunizations

The success of a vaccine in inducing a protective antibody response depends on the longevity of both long-lived plasma cells (PC) and memory B cells. We have previously shown that the in vivo antibody response to a new influenza vaccine, the ex vivo plasmablast response, the in vitro B cell function...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Frasca, Daniela, Diaz, Alain, Romero, Maria, Blomberg, Bonnie B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876633/
https://ncbi.nlm.nih.gov/pubmed/27108193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.04.023
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