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B Cell–Specific Biomarkers for Optimal Antibody Responses to Influenza Vaccination and Molecular Pathways That Reduce B Cell Function with Aging

This review highlights recent findings on the effects of aging on influenza vaccine responses, with major emphasis on T and B cells, which are significantly impaired by aging. We discuss changes in T cell production and thymic output; T cell subsets; and TCR repertoire, function, and response to lat...

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Detalhes bibliográficos
Publicado no:Crit Rev Immunol
Main Authors: Frasca, Daniela, Blomberg, Bonnie B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921867/
https://ncbi.nlm.nih.gov/pubmed/28845758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1615/CritRevImmunol.2017020113
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