METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing

Epigenetic alterations contributed to human carcinogenesis immensely. N6-methyladenosine (m6A) is one of the most preventive and abundant modifications on RNA molecules present in eukaryotes. However, the biological function of m6A methylation in colorectal cancer (CRC) remains largely unclear. Here...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Chen, Xiaoxiang, Xu, Mu, Xu, Xueni, Zeng, Kaixuan, Liu, Xiangxiang, Sun, Li, Pan, Bei, He, Bangshun, Pan, Yuqin, Sun, Huiling, Xia, Xinyi, Wang, Shukui
Format: Artigo
Langue:Inglês
Publié: American Society of Gene & Cell Therapy 2020
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001002/
https://ncbi.nlm.nih.gov/pubmed/31839484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.11.016
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