METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing

Epigenetic alterations contributed to human carcinogenesis immensely. N6-methyladenosine (m6A) is one of the most preventive and abundant modifications on RNA molecules present in eukaryotes. However, the biological function of m6A methylation in colorectal cancer (CRC) remains largely unclear. Here...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Chen, Xiaoxiang, Xu, Mu, Xu, Xueni, Zeng, Kaixuan, Liu, Xiangxiang, Sun, Li, Pan, Bei, He, Bangshun, Pan, Yuqin, Sun, Huiling, Xia, Xinyi, Wang, Shukui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001002/
https://ncbi.nlm.nih.gov/pubmed/31839484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.11.016
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