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METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing

Epigenetic alterations contributed to human carcinogenesis immensely. N6-methyladenosine (m6A) is one of the most preventive and abundant modifications on RNA molecules present in eukaryotes. However, the biological function of m6A methylation in colorectal cancer (CRC) remains largely unclear. Here...

詳細記述

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書誌詳細
出版年:Mol Ther
主要な著者: Chen, Xiaoxiang, Xu, Mu, Xu, Xueni, Zeng, Kaixuan, Liu, Xiangxiang, Sun, Li, Pan, Bei, He, Bangshun, Pan, Yuqin, Sun, Huiling, Xia, Xinyi, Wang, Shukui
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Gene & Cell Therapy 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001002/
https://ncbi.nlm.nih.gov/pubmed/31839484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.11.016
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