METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is one of the leading causes of tumor-related death worldwide, and its main cause of death is distant metastasis. Methyltransferase-like 14(METTL14), a major RNA N6-adenosine methyltransferase, is involved in tumor progression via regulating RNA function. The goal...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cancer
Auteurs principaux: Chen, Xiaoxiang, Xu, Mu, Xu, Xueni, Zeng, Kaixuan, Liu, Xiangxiang, Pan, Bei, Li, Chenmeng, Sun, Li, Qin, Jian, Xu, Tao, He, Bangshun, Pan, Yuqin, Sun, Huilin, Wang, Shukui
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7298962/
https://ncbi.nlm.nih.gov/pubmed/32552762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01220-7
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