MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy

BACKGROUND: Diabetic retinopathy (DR) is a main complication of diabetes mellitus (DM). Recent studies have implicated microRNAs in human retinal microvascular endothelial cell (HRMEC) dysfunction. In this study, we aim to investigate the apoptotic promotion of miR-29b-3p by blocking SIRT1 in HRMEC...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Zeng, Yong, Cui, Zekai, Liu, Jian, Chen, Jiansu, Tang, Shibo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000655/
https://ncbi.nlm.nih.gov/pubmed/32063865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01621
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