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MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy

BACKGROUND: Diabetic retinopathy (DR) is a main complication of diabetes mellitus (DM). Recent studies have implicated microRNAs in human retinal microvascular endothelial cell (HRMEC) dysfunction. In this study, we aim to investigate the apoptotic promotion of miR-29b-3p by blocking SIRT1 in HRMEC...

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Publicado en:Front Physiol
Main Authors: Zeng, Yong, Cui, Zekai, Liu, Jian, Chen, Jiansu, Tang, Shibo
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000655/
https://ncbi.nlm.nih.gov/pubmed/32063865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01621
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