MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy

BACKGROUND: Diabetic retinopathy (DR) is a main complication of diabetes mellitus (DM). Recent studies have implicated microRNAs in human retinal microvascular endothelial cell (HRMEC) dysfunction. In this study, we aim to investigate the apoptotic promotion of miR-29b-3p by blocking SIRT1 in HRMEC...

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Udgivet i:Front Physiol
Main Authors: Zeng, Yong, Cui, Zekai, Liu, Jian, Chen, Jiansu, Tang, Shibo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000655/
https://ncbi.nlm.nih.gov/pubmed/32063865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01621
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