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Degradation and modification of cochlear gap junction proteins in the early development of age-related hearing loss

Age-related hearing loss (ARHL) is the progressive, bilateral loss of high-frequency hearing in elderly people. Mutations in GJB2, encoding the cochlear gap junction protein connexin26 (Cx26), are the most frequent cause of hereditary deafness; however, a common molecular pathology between ARHL and...

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Publicado en:Exp Mol Med
Autores principales: Tajima, Shori, Danzaki, Keiko, Ikeda, Katsuhisa, Kamiya, Kazusaku
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000393/
https://ncbi.nlm.nih.gov/pubmed/31988333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0377-1
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