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Dominant negative connexin26 mutation R75W causing severe hearing loss influences normal programmed cell death in postnatal organ of Corti

BACKGROUND: The greater epithelial ridge (GER) is a developmental structure in the maturation of the organ of Corti. Situated near the inner hair cells of neonatal mice, the GER undergoes a wave of apoptosis after postnatal day 8 (P8). We evaluated the GER from P8 to P12 in transgenic mice that carr...

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Detalhes bibliográficos
Main Authors: Inoshita, Ayako, Karasawa, Keiko, Funakubo, Megumi, Miwa, Asuka, Ikeda, Katsuhisa, Kamiya, Kazusaku
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893426/
https://ncbi.nlm.nih.gov/pubmed/24387126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-15-1
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