Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice

BACKGROUND: Mutations in GJB2, which encodes connexin 26 (Cx26), a cochlear gap junction protein, represent a major cause of pre-lingual, non-syndromic deafness. The degeneration of the organ of Corti observed in Cx26 mutant—associated deafness is thought to be a secondary pathology of hearing loss....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Anzai, Takashi, Fukunaga, Ichiro, Hatakeyama, Kaori, Fujimoto, Ayumi, Kobayashi, Kazuma, Nishikawa, Atena, Aoki, Toru, Noda, Tetsuo, Minowa, Osamu, Ikeda, Katsuhisa, Kamiya, Kazusaku
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619622/
https://ncbi.nlm.nih.gov/pubmed/26492081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141258
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