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Targeted connexin26 ablation arrests postnatal development of the organ of Corti

Mutations in the gene coding for connexin26 (Cx26) is the most common cause of human nonsyndromic hereditary deafness. To investigate deafness mechanisms underlying Cx26 null mutations, we generated three independent lines of conditional Cx26 null mice. Cell differentiation and gross cochlear morpho...

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Autors principals: Wang, Yunfeng, Chang, Qing, Tang, Wenxue, Sun, Yu, Zhou, Binfei, Li, Huawei, Lin, Xi
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713729/
https://ncbi.nlm.nih.gov/pubmed/19433060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.023
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