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Early developmental expression of connexin26 in the cochlea contributes to its dominate functional role in the cochlear gap junctions
Mutations in Gjb2 and Gjb6 genes, coding for connexin26 (Cx26) and Cx30 proteins respectively, are linked to about half of all cases of human autosomal non-syndromic prelingual deafness. Molecular mechanisms of the hearing impairments, however, are unclear. Most cochlear gap junctions (GJs) are co-a...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259187/ https://ncbi.nlm.nih.gov/pubmed/22142852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.11.093 |
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