Implementation and use of whole exome sequencing for metastatic solid cancer

BACKGROUND: Genomically-guided clinical trials are performed across different tumor types sharing genetic mutations, but trial organization remains complex. Here we address the feasibility and utility of routine somatic and constitutional exome analysis in metastatic cancer patients. METHODS: Exoma...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Réda, Manon, Richard, Corentin, Bertaut, Aurelie, Niogret, Julie, Collot, Thomas, Fumet, Jean David, Blanc, Julie, Truntzer, Caroline, Desmoulins, Isabelle, Ladoire, Sylvain, Hennequin, Audrey, Favier, Laure, Bengrine, Leila, Vincent, Julie, Hervieu, Alice, Dusserre, Jean-Florian Guion, Lepage, Come, Foucher, Pascal, Borg, Christophe, Albuisson, Juliette, Arnould, Laurent, Nambot, Sophie, Faivre, Laurence, Boidot, Romain, Ghiringhelli, Francois
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Research paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000332/
https://ncbi.nlm.nih.gov/pubmed/31923800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.102624
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