Implementation and use of whole exome sequencing for metastatic solid cancer

BACKGROUND: Genomically-guided clinical trials are performed across different tumor types sharing genetic mutations, but trial organization remains complex. Here we address the feasibility and utility of routine somatic and constitutional exome analysis in metastatic cancer patients. METHODS: Exoma...

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Vydáno v:EBioMedicine
Hlavní autoři: Réda, Manon, Richard, Corentin, Bertaut, Aurelie, Niogret, Julie, Collot, Thomas, Fumet, Jean David, Blanc, Julie, Truntzer, Caroline, Desmoulins, Isabelle, Ladoire, Sylvain, Hennequin, Audrey, Favier, Laure, Bengrine, Leila, Vincent, Julie, Hervieu, Alice, Dusserre, Jean-Florian Guion, Lepage, Come, Foucher, Pascal, Borg, Christophe, Albuisson, Juliette, Arnould, Laurent, Nambot, Sophie, Faivre, Laurence, Boidot, Romain, Ghiringhelli, Francois
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000332/
https://ncbi.nlm.nih.gov/pubmed/31923800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.102624
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