Implementation and use of whole exome sequencing for metastatic solid cancer

BACKGROUND: Genomically-guided clinical trials are performed across different tumor types sharing genetic mutations, but trial organization remains complex. Here we address the feasibility and utility of routine somatic and constitutional exome analysis in metastatic cancer patients. METHODS: Exoma...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Réda, Manon, Richard, Corentin, Bertaut, Aurelie, Niogret, Julie, Collot, Thomas, Fumet, Jean David, Blanc, Julie, Truntzer, Caroline, Desmoulins, Isabelle, Ladoire, Sylvain, Hennequin, Audrey, Favier, Laure, Bengrine, Leila, Vincent, Julie, Hervieu, Alice, Dusserre, Jean-Florian Guion, Lepage, Come, Foucher, Pascal, Borg, Christophe, Albuisson, Juliette, Arnould, Laurent, Nambot, Sophie, Faivre, Laurence, Boidot, Romain, Ghiringhelli, Francois
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000332/
https://ncbi.nlm.nih.gov/pubmed/31923800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.102624
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