RAS status and neoadjuvant chemotherapy impact CD8+ cells and tumor HLA class I expression in liver metastatic colorectal cancer

BACKGROUND: T lymphocytes and HLA expression on tumor cell both influence prognostic of localized colorectal cancer, but their role following chemotherapy in patients with liver metastatic colorectal cancer (mCRC) was not addressed. METHODS: One hundred fourteen patients treated in curative intend o...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Ledys, Fanny, Klopfenstein, Quentin, Truntzer, Caroline, Arnould, Laurent, Vincent, Julie, Bengrine, Leila, Remark, Romain, Boidot, Romain, Ladoire, Sylvain, Ghiringhelli, Francois, Derangere, Valentin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245855/
https://ncbi.nlm.nih.gov/pubmed/30454021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0438-3
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