Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment

The immune checkpoint blockade (ICB) immunotherapy has prolonged overall survival for cancer patients but the response rates are low. The resistance to ICB is likely due to compensatory upregulation of additional immune inhibitory molecules. In this study, we first systematically examined Tim-3 expr...

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Dades bibliogràfiques
Publicat a:Oncoimmunology
Autors principals: Yang, Min, Du, Wenwen, Yi, Lixian, Wu, Shaoxian, He, Chunyan, Zhai, Wensi, Yue, Cuihua, Sun, Runzi, Menk, Ashley V., Delgoffe, Greg M., Jiang, Jingting, Lu, Binfeng
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999836/
https://ncbi.nlm.nih.gov/pubmed/32076578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1708064
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