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Elevated pCO(2) affects the lactate metabolic shift in CHO cell culture processes
The shift from lactate production to consumption in CHO cell metabolism is a key event during cell culture cultivations and is connected to increased culture longevity and final product titers. However, the mechanisms controlling this metabolic shift are not yet fully understood. Variations in lacta...
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| Veröffentlicht in: | Eng Life Sci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6999464/ https://ncbi.nlm.nih.gov/pubmed/32624899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elsc.201700131 |
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