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Investigation of the interactions of critical scale-up parameters (pH, pO(2) and pCO(2)) on CHO batch performance and critical quality attributes
Understanding process parameter interactions and their effects on mammalian cell cultivations is an essential requirement for robust process scale-up. Furthermore, knowledge of the relationship between the process parameters and the product critical quality attributes (CQAs) is necessary to satisfy...
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| Publicado no: | Bioprocess Biosyst Eng |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5274649/ https://ncbi.nlm.nih.gov/pubmed/27752770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00449-016-1693-7 |
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