Alpha-synuclein fragments trigger distinct aggregation pathways

Aggregation of alpha-synuclein (αSyn) is a crucial event underlying the pathophysiology of synucleinopathies. The existence of various intracellular and extracellular αSyn species, including cleaved αSyn, complicates the quest for an appropriate therapeutic target. Hence, to develop efficient diseas...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Death Dis
मुख्य लेखकों: Chakroun, Tasnim, Evsyukov, Valentin, Nykänen, Niko-Petteri, Höllerhage, Matthias, Schmidt, Andreas, Kamp, Frits, Ruf, Viktoria C., Wurst, Wolfgang, Rösler, Thomas W., Höglinger, Günter U.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997403/
https://ncbi.nlm.nih.gov/pubmed/32015326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2285-7
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