Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models

Extracellular matrix (ECM) plays an important role in tumor development and dissemination, but few points of therapeutic intervention targeting ECM of the tumor microenvironment have been exploited to date. Recent observations suggest that the enzymatic introduction of disulfide bond cross-links int...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Feldman, Tal, Grossman-Haham, Iris, Elkis, Yoav, Vilela, Patrick, Moskovits, Neta, Barshack, Iris, Salame, Tomer M., Fass, Deborah, Ilani, Tal
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996906/
https://ncbi.nlm.nih.gov/pubmed/32064042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27438
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